NASDAQ: VRTX       Vertex Pharmaceutic
Last Price Today's Change   Day's Range   Trading Volume
223.31   -4.77 (2.09%)  221.72 - 229.00  1,470,596


Avg Volume (4 weeks):1,675,897
4 Weeks Range:214.66 - 232.49
4 Weeks Price Volatility (%):
52 Weeks Range:178.21 - 242.99
52 Weeks Price Volatility (%):
Average Price Target: 141.00
Price Target Upside/Downside: -82.31


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Business Background

Vertex Pharmaceuticals Incorporated is engaged in discovering, developing, manufacturing and commercializing medicines for serious diseases. The Company is focused on developing and commercializing therapies for the treatment of cystic fibrosis (CF) and advancing its research and development programs in other indications. The Company's marketed medicines are ORKAMBI and KALYDECO. ORKAMBI (lumacaftor in combination with ivacaftor) is approved as a treatment for patients having two copies (homozygous) of the Delta-F508 (F508del) mutation in their cystic fibrosis transmembrane conductance regulator (CFTR) gene. KALYDECO (ivacaftor) is approved for the treatment of CF patients having the G551D mutation or other specified mutations in their CFTR gene. The Company's development programs in the field of CF include Tezacaftor (VX-661), VX-152, VX-440, VX-659, VX-445 and VX-371. VX-152, VX-440, VX-659 and VX-445 are CFTR corrector compounds.

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